Mosquito sterilization, opportunity to control Chikungunya, Dengue, Zika- WHO

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The World Health Orgaization (WHO), says a technique that sterilizes male mosquitoes using radiation will soon be tested as part of global health efforts to control diseases such as chikungunya, dengue and Zika.

The Sterile Insect Technique (SIT) is a form of insect birth control.  The process involves rearing large quantities of sterilized male mosquitoes in dedicated facilities, and then releasing them to mate with females in the wild. As they do not produce any offspring, the insect population declines over time.

The Special Programme for Research and Training in Tropical Diseases (TDR), and the International Atomic Energy Agency (IAEA), in partnership with the Food and Agriculture Organization of the United Nations (FAO), and WHO have developed a guidance document for countries that have expressed interest in testing the Sterile Insect Technique (SIT) for Aedes mosquitoes.

WHO Chief Scientist, Dr Soumya Swaminathan, said “Half the world’s population is now at risk of dengue. And despite our best efforts, current efforts to control it are falling short. We desperately need new approaches and this initiative is both promising and exciting.”

In recent decades, the incidence of dengue has increased dramatically due to environmental changes, unregulated urbanization, transport and travel, and insufficient sustainable vector control tools and their application, WHO said.

Dengue outbreaks are currently occurring in several countries, notably on the Indian sub-continent.

Bangladesh is facing the worst outbreak of dengue since its first recorded epidemic in 2000.

The South Asian nation has seen the number of cases rise to over 92,000 since January 2019, with daily admissions peaking at more than 1,500 new dengue patients in hospitals in recent weeks and is one of the countries to express interest in the Sterile Insect Technique.

Diseases transmitted by mosquitoes such as malaria, dengue, Zika, chikungunya, and yellow fever account for about 17% of all infectious diseases globally, claiming more than 700,000 lives each year, and inflicting suffering on many more.

The 2015 outbreak of Zika in Brazil was linked to an increase in the number of babies being born with microcephaly.

Sterile Insect Technique was first developed by the US Department of Agriculture and has been used successfully to target insect pests that attack crops and livestock, such as the Mediterranean fruit fly and the New World screwworm fly. It is currently in use globally in the agriculture sector on six continents.

The guidance on using the technique to control diseases in humans recommends adopting a phased approach that allows time to test the efficacy of the sterilized insects.

TDR is a Special global Programme for Research and Training in Tropical Diseases, that helps facilitate, support and influence efforts to combat diseases of poverty.

 

It is co-sponsored by the United Nations Children’s Fund (UNICEF), the United Nations Development Programme (UNDP), the World Bank and WHO.

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